Oropharyngeal cancer: late recurrence associated with late survival and HPV status
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- Survival beyond two years and HPV-positive tumor status correlate with later recurrence in oropharyngeal squamous cell carcinoma (OPSCC) patients.
- HPV-positive patients had longer time to recurrence in late (≥24 months) survivors compared with HPV-negative patients (median 21.8 months vs. 13.8 months, p=.028).
- Late survivors had later recurrence regardless of HPV status, suggesting a survival bias for late recurrence.