Oropharyngeal cancer: new nomograms for survival and progression

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  • Novel nomograms for OS, time to progression (TTP), and survival after progression (SAP) for human papillomavirus (HPV)-positive and HPV-negative patients with oropharyngeal squamous cell carcinoma (OPSCC) are presented.

Why this matters

  • This is the first study to combine tumor and clinical factors to construct nomograms for OS, TTP, and SAF in patients with OPSCC.

Key results

  • 5 y OS was 77% in HPV-positive patients and 30% in HPV-negative patients (P<.01).
  • Smoking pack years, treatment type, tumor location, and TNM classification were also associated with OS (P<.05).
  • Median TTP was longer in the HPV-positive patients (13 vs 8.5 mo; P<.05).
  • Smoking and TNM classification were also associated with TTP (P<.05).
  • Median SAP was longer in HPV-pos...