Oropharyngeal cancer: new nomograms for survival and progression
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Novel nomograms for OS, time to progression (TTP), and survival after progression (SAP) for human papillomavirus (HPV)-positive and HPV-negative patients with oropharyngeal squamous cell carcinoma (OPSCC) are presented.
Why this matters
This is the first study to combine tumor and clinical factors to construct nomograms for OS, TTP, and SAF in patients with OPSCC.
5 y OS was 77% in HPV-positive patients and 30% in HPV-negative patients (P<.01).
Smoking pack years, treatment type, tumor location, and TNM classification were also associated with OS (P<.05).
Median TTP was longer in the HPV-positive patients (13 vs 8.5 mo; P<.05).
Smoking and TNM classification were also associated with TTP (P<.05).