OSCC progression and prognosis associated with matriptase-2 expression

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Takeaway

  • Reduced expression of matriptase-2 is associated with tumor progression and poor survival of oral squamous cell carcinoma (OSCC) patients.

Key results

  • Low expression of matriptase-2 was significantly associated with poorly differentiated tumors (p=.001), larger tumor size (p=.017), positive nodal stage (p=.008), distant metastasis (p=.032), late clinical stage (p=.001), and poor s...