Pneumonia-related ARDS: the significance of coinfection
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- Coinfection with a virus and another pathogen is not unusual and is associated with higher hospital mortality.
Why this matters
- The effect of causal pathogens on the outcomes of pneumonia-related acute respiratory distress syndrome (ARDS) should be addressed because most pathogens are potentially treatable.
- Prospective, observational cohort study.
- Adult patients with pneumonia-related ARDS receiving bronchoalveolar lavage (BAL) after negative tracheal aspirate or sputum culture.
- All patients received empiric antimicrobials before BAL.
- Funding: None.
- 255 patients.
- 55.7% were pathogen-positive, of whom 39.8% had bacterial, 62% had viral, and 57% had fungal pathogens.
- Most common gram-negative and gram-positive bacteria were Pseudomonas aeruginosa and methicillin-resistant Staphylococ...