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Clinical Summary

Postherpetic neuralgia: tradeoff seen between pregabalin and gabapentin

Susan London   |   17 November 2022

Takeaway

  • For the treatment of postherpetic neuralgia, pregabalin was more efficacious than gabapentin for reducing pain and sleep disturbance but also had more adverse effects.

Why this matters

  • About 20% of patients with herpes zoster develop postherpetic neuralgia, and optimal first-line therapy is uncertain.

Study design

  • Meta-analysis of 14 randomised...

          

Topic Challenges

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