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Prevención del cáncer de mama: el genotipo metabolizador de fármacos pronostica la respuesta al tamoxifeno y la interrupción del fármaco

Univadis | Clinical Summary | 26 July 2021

Según un análisis secundario del ensayo KARISMA, con el genotipo de metabolización malo es menos probable que se obtenga respuesta al tamoxifeno.

Punto clave

Las pacientes con el genotipo de mal metabolismo de la enzima hepática CYP2D6 tienen menos probabilidades de obtener respuesta al tamoxifeno para la prevención del cáncer de mama.
Las personas con el genotipo de metabolismo del CYP2D6 ultrarrápido pueden experimentar efectos adversos fuertes y es más probable que...

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