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A large population cohort shows an increased risk for fracture in patients taking selective serotonin reuptake inhibitors (SSRIs), antipsychotics, and benzodiazepines.
Why this matters
The study suggests that psychotropic medication use is a risk factor for fractures.
The researchers analyzed data from 68,730 individuals (62,275 women; age, 40 y and older) who underwent a baseline bone mineral density assessment between January 1, 1996 and March 28, 2013. Fracture risk was assessed on March 28, 2013.
Funding: None disclosed.
18.9% of participants had mental disorders, and 17.4% used psychotropic medications.