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Sacubitril/valsartan may benefit patients with heart failure and diabetes

Miriam Tucker | Clinical Summary | 24 June 2022

Study finds modest HbA1c reduction, low hypoglycemia occurrence, and reduced insulin need.

Takeaway

Modest glucose-lowering effect of sacubitril/valsartan via reduced HbA1c and insulin initiation was similar in heart failure (HF) patients with diabetes across left ventricular ejection fraction (LVEF) spectrum.
Low hypoglycemia risk.

Why this matters

Diabetes is common in patients with HF with preserved ejection fraction.
Diabetes and elevated HbA1c are...

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Sacubitril/valsartan may benefit patients with heart failure and diabetes

December Challenge

What are the maternal risk factors for cerebral palsy in children?

Are assisted reproductive technologies associated with an increased risk for cardiovascular disease in nulliparous women?

How do different dosages of gabapentin affect pain intensity in patients undergoing spine surgery?

Does the Mediterranean diet have protective effects on adverse pregnancy outcomes?

What is the most effective digitally assisted intervention to reduce glycated haemoglobin?

How effective is endoscopic screening in reducing the risk for gastric cancer mortality?

What is the association between apolipoproteins and metabolic syndrome?

Can tumour-infiltrating lymphocyte scores affect treatment decisions?

Do different exercise training modes have different effects on resting blood pressure?

How are neurocutaneous syndromes associated with central nervous system tumours in childhood?

Topic Challenges

Quiz challenge Emerging diseases: COVID-19

ESMO 2020 topic challenge

Women's health challenge

Antibiotics - Consequence of MDR carriage

Neurological disorders challenge

Rheumatology challenge

Lyme Disease

Mental health challenge

Topic challenge - Children conditions

Lyme Disease