Taller people are at increased risk for colorectal, lung cancers

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Takeaway
  • A 10 cm increase in adult height was associated with 58% increased odds for colorectal cancer and 10% increased odds for lung cancer.

Key results

  • A 10 cm increase was associated with a relative risk (RR) of 1.12 (95% CI, 1.10-1.15) for colorectal cancer, 1.07 (95% CI, 1.05-1.10) for prostate cancer, and 1.06 (95% CI, 1.02-1.11) for lung cancer. 
  • Odds ratios (ORs) were increased for colorectal cancer (OR, 1.58; 95% CI 1.14-2.18) and lung cancer (OR, 1.10; 95% CI, 1.00-1.22), but not prostate cancer (OR, 1.03; 95% CI, 0.92-1.15). 
  • RR for rectal cancer was lower (RR, 1.10; 95% CI 1.06-1.13) than for colon cancer (RR, 1.17; 95% CI, 1.14-1.19). 
  • OR for lung adenocarcinoma was higher (OR, 1.16; 95% CI, 1.00-1.35; P=.056) than the OR for squamous cell carcinoma (OR, 1.06; 95% CI, 0.90-1.25; P=.463).

Study design

  • Systematic review and meta-analysis of 62 prospective studies...