Takeaway

• Tenofovir disoproxil fumarate reduces progression and late complications risk in patients with noncirrhotic chronic hepatitis B (HepB) and minimally raised s erum alanine aminotransferase (ALT).
• Effect on necroinflammation is insignificant.

Why this matters

• Nucleoside and nucleotide analogs such as tenofovir disoproxil fumarate may...