Thyroid cancer pathology associated with FGF19 expression

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Takeaway

  • Overexpression of fibroblast growth factor (FGF) 19 is significantly associated with advanced pathological features of thyroid cancer tumors.

Key results

  • FGF19 expression was detected in 82% of thyroid cancer tissues.
  • FGF19 overexpression was significantly associated with advanced metastatic stage (p=.008), extrathyroidal invasion (p=.01), lymph node metastasis (p=.01), and distant metastasis (p=.02).
  • FGF19 knockdown suppressed thyroid cancer cell ...