- In patients referred for stress testing, decreasing exercise time was associated with increased risk of death in both genders.
Why this matters
- Physical inactivity is a major health problem.
- A total of 126,356 patients (mean age 53.5 years, 59% were male) were included; at 10-year follow-up, 9929 (8%) had died.
- Median exercise time was 570 seconds in males and 480 seconds in females.
- Using the median exercise time of 540 seconds, lower exercise time was associated with a higher risk of death (hazard ratio [HR] 1.22; P <0.001].
- After adjusting for cardiac risk factors, an exercise time <540 seconds conferred about a two-fold increased risk of death (HR 2.06; P <0.001] and was the major determinant of death after age.
Study design ...