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Type 2 diabetes: what do SGLT-2 inhibitors do to body composition?

Miriam Tucker   |   Clinical Summary   |   12 January 2023
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SGLT-2is improve several parameters including weight and BMI, but may also reduce muscle mass.

Takeaway

  • Sodium-glucose cotransporter 2 inhibitors (SGLT-2is) improve body composition in type 2 diabetes (T2D), including body weight, BMI, waist circumference (WC), visceral fat area, subcutaneous fat area, percentage body fat, and fat mass reduction.
  • However, adversely,...

          

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