Uncontrolled asthma: is adjunct anti-leukotriene better than increased ICS dose?

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Takeaway
  • In adults and adolescents with uncontrolled asthma receiving daily inhaled corticosteroid (ICS), adding leukotriene receptor antagonist (LTRA) reduced exacerbation and improved lung function and control compared with same dose ICS alone. 
  • No evidence of superiority vs increased dose IC...