We screened 366 studies on Vaccines this month. These are the most important.
"Dose sparing" investigational influenza vaccine is safe, immunogenic
- A novel, "dose sparing" whole-virion influenza vaccine has been found safe and immunogenic at all doses tested (range, 3.5-15 μg hemagglutinin protein per strain) in both adults and elderly patients.
- At times of epidemics or vaccine shortages, lower-dose vaccines will boost availability.
DTaP vaccination during pregnancy prevents infant pertussis
- Pertussis infection is especially virulent in infants.
- DTaP vaccination during pregnancy is successful at preventing pertussis in infants during the first 2 mo (before the time of their own DTaP vaccination) and first year of life.
HPV vaccine not linked to adverse pregnancy outcomes
- A large study found no association between exposure to the quadrivalent HPV vaccine and adverse pregnancy outcome, including major birth defects and spontaneous abortion.
- A prior study linked HPV vaccination to spontaneous abortion, but it was small in size.
Other recent Vitals: