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Smokers switching to e-cigarettes (“vaping”) long-term have a significantly reduced exposure to carcinogens.
E-cigarettes are likely to be beneficial only with complete cessation of combustible cigarettes.
Why this matters
E-cigarettes are increasingly popular, but long-term safety data is scarce.
Cross-sectional study (n=181) of smokers, smokers also using e-cigarettes or nicotine replacement therapy (NRT) for ≥6 mo (dual users), and smokers who had switched entirely to e-cigarettes or NRT for ≥6 mo.
Urine and saliva samples were analyzed for metabolites of nicotine, tobacco-specific N-nitrosamines (TSNAs), and volatile organic compounds (VOCs).
Funding: Cancer Research UK.
Nicotine intake was consistent across groups after controlling for confounders.
Compared with smokers or dual users, e-cigarette and NRT users had significantly lower levels of the carcinogenic N-n...