Vaping appears safer than smoking cigarettes

Access to the full content of this site is available only to registered healthcare professionals. Register to read more

Takeaway

  • Smokers switching to e-cigarettes (“vaping”) long-term have a significantly reduced exposure to carcinogens.
  • E-cigarettes are likely to be beneficial only with complete cessation of combustible cigarettes.

Why this matters

  • E-cigarettes are increasingly popular, but long-term safety data is scarce.

Study design

  • Cross-sectional study (n=181) of smokers, smokers also using e-cigarettes or nicotine replacement therapy (NRT) for ≥6 mo (dual users), and smokers who had switched entirely to e-cigarettes or NRT for ≥6 mo.
  • Urine and saliva samples were analyzed for metabolites of nicotine, tobacco-specific N-nitrosamines (TSNAs), and volatile organic compounds (VOCs).
  • Funding: Cancer Research UK.

Key results

  • Nicotine intake was consistent across groups after controlling for confounders.
  • Compared with smokers or dual users, e-cigarette and NRT users had significantly lower levels of the carcinogenic N-n...