What is the magic number for DAPT with EES?

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  • In patients with everolimus-eluting stents (EES), continuing dual antiplatelet therapy (DAPT) beyond 2 y offers no additional protection against major adverse cardiac and cerebral events (MACCE) compared to stopping DAPT at 2 y.

Why this matters

  • Although DAPT is common after EES implantation, there is no consensus on how long the therapy should be continued.

Study design

  • 742 patients underwent successful percutaneous coronary intervention (PCI) with EES and were free from MACCE at 2 y post PCI.
  • 591 of those received DAPT for 2 y and 151 received DAPT for ≤2 y.
  • 3 y follow-up.
  • Funding: None disclosed.

Key results

  • After adjusting for baseline differences, 145 patients from each group were propensity matched.
  • ...