What's the best surgical management for Crohn's disease?
Access to the full content of this site is available only to registered healthcare professionals.
Register to read more
- Subtotal colectomy and ileorectal anastomosis (STC) and segmental colectomy (SC) are both effective methods of surgical management of Crohn's disease (CD).
Why this matters
- Although total proctocolectomy (TPC) is considered highly effective, this meta-analysis suggests STC and SC may be preferable.
- There was no difference in overall or surgical recurrence of CD between STC and SC patients (OR, 1.24).
- STC had higher overall and surgical recurrence risk compared with TPC (OR, 3.53 [P<.0001]; OR, 3.52 [P<.0001], respectively).
- SC had a higher risk for adverse events than STC (OR, 2.84; P=.02), and STC had a lower risk than TPC (OR, 0.19; P<.0001).
- SC had a lower incidence of stoma formation than STC (OR, 0.26;...