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What's the best metformin alternative in type 2 diabetes?

Miriam Tucker   |   Clinical Summary   |   23 December 2022
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Takeaway

  • For patients with type 2 diabetes (T2D) who cannot take metformin, a meta-analysis suggests glucagon-like peptide-1 receptor agonists (GLP-1RAs) may be the best overall first-line alternative based on efficacy and safety, but other agents may better meet individual needs.

Why this matters

  • Clinical guidelines for T2D recommend metformin as...

          

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